Tools · Computational Biology

OpenDDE

Predict protein, nucleic acid, and small-molecule complex structures with OpenDDE

Hardware and price

Price per run

What a typical run reserves from your wallet: the catalog's expected runtime on each piece of hardware × your plan's per-second rate. Larger inputs reserve more, and you're charged only for the seconds the job actually runs.

OpenDDE: reservation per run, USD
Hardware	Typical runtime	Basic	Starter	Pro	Enterprise
Nvidia A10Default	30 min	$1.93	$1.37	$1.10	$0.83
Nvidia L40S	30 min	$3.42	$2.45	$1.94	$1.46
Nvidia A100, 40 GB	30 min	$3.67	$2.63	$2.11	$1.58
Nvidia A100, 80 GB	30 min	$4.37	$3.13	$2.50	$1.87
Nvidia H100	30 min	$6.91	$4.93	$3.94	$2.97
Nvidia H200	30 min	$7.94	$5.67	$4.54	$3.40
Nvidia B200	30 min	$10.94	$7.81	$6.25	$4.70

In workflows

Chain it with other steps.

Each input and output has a data kind, so the builder only connects steps that fit.

Inputs

None

Outputs

ArchiveZIP
StructuresPDB

References

The method behind it.

Aureka AI OpenDDE project (2026). Folding, Reasoning, and Scaling with Open-source Drug Discovery Engine. arXiv. doi:10.48550/arxiv.2607.03787 (opens in a new tab)

Run via API

Submit it from your own code.

Use an API key from your account. The estimate uses your plan's rates; submitting reserves that amount from your wallet.

# Estimate the reservation for your plan (payload fields: see the API reference)
curl -X POST https://api.cognichem.com/api/v1/jobs/estimate \
  -H "X-Api-Key: $COGNICHEM_API_KEY" \
  -H "Content-Type: application/json" \
  -d '{"job_type": "opendde", "resource": "a10", "payload": {}}'

# Submit (retrying with the same Idempotency-Key never submits twice)
curl -X POST https://api.cognichem.com/api/v1/jobs/submit \
  -H "X-Api-Key: $COGNICHEM_API_KEY" \
  -H "Idempotency-Key: $(uuidgen)" \
  -H "Content-Type: application/json" \
  -d '{"job_name": "opendde-1", "job_type": "opendde", "resource": "a10", "payload": { ... }}'

Payload fields and examples in the docs

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All tools

Price per run

Chain it with other steps.

The method behind it.

Submit it from your own code.

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