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Tools · Computational Biology

Sequence Mutator

Apply point mutations such as T315I to a protein sequence, checking each wild-type residue

Open in the appRun via API

Hardware and price

Price per run

What a typical run reserves from your wallet: the catalog's expected runtime on each piece of hardware × your plan's per-second rate. Larger inputs reserve more, and you're charged only for the seconds the job actually runs.

Sequence Mutator: reservation per run, USD
HardwareTypical runtimeBasicStarterProEnterprise
CPUDefault1 min$0.0084$0.0048$0.003$0.0018

In workflows

Chain it with other steps.

Each input and output has a data kind, so the builder only connects steps that fit.

Inputs

  • Protein sequences · optionalFASTA, RAW

Outputs

  • ArchiveZIP
  • Protein sequencesFASTA
  • Protein sequencesFASTA

Ready-made workflows that use it

References

The method behind it.

  1. Johan T. den Dunnen, Raymond Dalgleish, Donna R. Maglott et al. (2016). HGVS Recommendations for the Description of Sequence Variants: 2016 Update. Human Mutation. doi:10.1002/humu.22981 (opens in a new tab)

Run via API

Submit it from your own code.

Use an API key from your account. The estimate uses your plan's rates; submitting reserves that amount from your wallet.

# Estimate the reservation for your plan (payload fields: see the API reference)
curl -X POST https://api.cognichem.com/api/v1/jobs/estimate \
  -H "X-Api-Key: $COGNICHEM_API_KEY" \
  -H "Content-Type: application/json" \
  -d '{"job_type": "sequence-mutate", "resource": "cpu", "payload": {}}'

# Submit (retrying with the same Idempotency-Key never submits twice)
curl -X POST https://api.cognichem.com/api/v1/jobs/submit \
  -H "X-Api-Key: $COGNICHEM_API_KEY" \
  -H "Idempotency-Key: $(uuidgen)" \
  -H "Content-Type: application/json" \
  -d '{"job_name": "sequence-mutate-1", "job_type": "sequence-mutate", "resource": "cpu", "payload": { ... }}'
Payload fields and examples in the docs

Computational Biology

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