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Evo 2

Genome modeling and design across all domains of life with the Evo 2 DNA language model

Open in the appRun via API

Hardware and price

Price per run

What a typical run reserves from your wallet: the catalog's expected runtime on each piece of hardware × your plan's per-second rate. Larger inputs reserve more, and you're charged only for the seconds the job actually runs.

Evo 2: reservation per run, USD
HardwareTypical runtimeBasicStarterProEnterprise
Nvidia L41 h$2.81$2.02$1.58$1.19
Nvidia A10Default1 h$3.85$2.74$2.20$1.66
Nvidia L40S1 h$6.84$4.90$3.89$2.92
Nvidia A100, 40 GB1 h$7.34$5.26$4.21$3.17
Nvidia A100, 80 GB1 h$8.75$6.26$5.00$3.74
Nvidia H1001 h$13.82$9.86$7.88$5.94
Nvidia H2001 h$15.88$11.34$9.07$6.80
Nvidia B2001 h$21.89$15.62$12.49$9.40

In workflows

Chain it with other steps.

Each input and output has a data kind, so the builder only connects steps that fit.

Inputs

None

Outputs

  • ArchiveZIP
  • TableCSV
  • SequencesFASTA

References

The method behind it.

  1. Garyk Brixi, Matthew G. Durrant, Jerome Ku et al. (2026). Genome modelling and design across all domains of life with Evo 2. Nature. doi:10.1038/s41586-026-10176-5 (opens in a new tab)

Run via API

Submit it from your own code.

Use an API key from your account. The estimate uses your plan's rates; submitting reserves that amount from your wallet.

# Estimate the reservation for your plan (payload fields: see the API reference)
curl -X POST https://api.cognichem.com/api/v1/jobs/estimate \
  -H "X-Api-Key: $COGNICHEM_API_KEY" \
  -H "Content-Type: application/json" \
  -d '{"job_type": "evo2", "resource": "a10", "payload": {}}'

# Submit (retrying with the same Idempotency-Key never submits twice)
curl -X POST https://api.cognichem.com/api/v1/jobs/submit \
  -H "X-Api-Key: $COGNICHEM_API_KEY" \
  -H "Idempotency-Key: $(uuidgen)" \
  -H "Content-Type: application/json" \
  -d '{"job_name": "evo2-1", "job_type": "evo2", "resource": "a10", "payload": { ... }}'
Payload fields and examples in the docs

Computational Biology

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